S1E11 - From Mouse to Human Trials

Season 1: The Science of Aging | Episode 11: From Mouse to Human Trials

Welcome to The Deep Dive, where we explore the multifaceted world of extending healthy human life. In this episode, we dive into the intriguing field of geroscience, examining the biological, scientific, and socio-economic dimensions of aging. Our discussion is guided by insights from leading experts who are shaping the future of healthy longevity through groundbreaking research and trials.

We tackle the crucial disconnect between successful laboratory findings and their translation into human benefits, often resulting in 'beautiful failures.' Our conversation highlights how regulatory perspectives influence drug development and shine a light on the critical distinction between biomarkers and surrogate endpoints.

The episode explores innovative trial designs aimed at measuring genuine health benefits and addresses the unique safety challenges posed by anti-aging therapies. We also discuss the broader economic and policy implications, considering how to make extended health spans accessible to all.

Join us as we unravel the complexities of age-related research, aiming to transform the dream of healthy longevity into reality.